Photo by Kevin Butz on UnsplashRegular coffee or caffeine consumption may offer a protective effect against developing multiple cardiometabolic diseases like coronary heart disease and stroke, the most common killers in human society today.
Detailed in new research published in the Endocrine Society, three cups of coffee per day were associated with those in the study cohort who had a lower profile for a novel risk marker called “new-onset cardiometabolic multimorbidity.”
Cardiometabolic multimorbidity (CM) refers to the coexistence of at least two cardiometabolic diseases, and the prevalence of individuals with CM is becoming an increasing public health concern as populations age around the world, notes the study.
The COVID-19 pandemic showed that the burden of co-morbidities in high-income countries means that swaths of the population are at all times especially vulnerable to novel infections, particularly upper respiratory tract infections.
Coffee and caffeine consumption could play an important protective role in almost all phases of CM development, the researchers from China and Sweden found.
“Consuming three cups of coffee, or 200-300 mg caffeine, per day might help to reduce the risk of developing cardiometabolic multimorbidity in individuals without any cardiometabolic disease,” said the study’s lead author Chaofu Ke, M.D., Ph.D. at Suzhou Medical College of Soochow University, in Suzhou, China.
The study found that compared with non-consumers or consumers of less than 100mg caffeine per day, consumers of a moderate amount of coffee (3 drinks per day) or caffeine (200-300 mg per day) had a 48.1% or 40.7% reduced risk for new-onset CM.
Dr. Ke and his colleagues based their findings on data from the UK Biobank, a large and detailed longitudinal dietary study with over 500,000 participants aged 37-73. The study excluded individuals who had ambiguous information on caffeine intake.
The resulting pool of participants included a total of 172,315 individuals who were free of any cardiometabolic diseases at baseline for the analyses of caffeine, and a corresponding 188,091 individuals for the analyses of coffee and tea consumption.
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The participants’ cardiometabolic diseases outcomes were identified from self-reported medical conditions, primary care data, linked inpatient hospital data, and death registry records linked to the UK Biobank.
Coffee and caffeine intake at all levels were inversely associated with the risk of new-onset CM in participants without cardiometabolic diseases. Those who reported moderate coffee or caffeine intake had the lowest risk, the study found. Moderate coffee or caffeine intake was inversely associated with almost all developmental stages of CM.
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“The findings highlight that promoting moderate amounts of coffee or caffeine intake as a dietary habit to healthy people might have far-reaching benefits for the prevention of CM,” Ke said.
Numerous epidemiological studies have revealed the protective effects of coffee, tea, and caffeine consumption, some of which GNN has reported on before.
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